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Xénon Aviation , a company based in Monterblanc, France, specialized in providing maritime surveillance services, maritime surveillance training, flight services and maintenance support, http://www.xenon-aviation.com
and
MChE Trading have signed a co-operation agreement with the aim to market cost efficient solutions for airborne fishery and coastal maritime surveillance systems as well as airborne search and rescue and maritime traffic surveillance tools
MChE Trading in co-operation wirh i2i associaes founded the LembergHighTech cluster http://www.lemberghightech.com. Lviv , a university city with long tradition, is the center of a region full of knowledge, skills and enterpreuneurship. There is a multitude of ambitious small and medium enterprises that can provide services like IT oustsourcing, assembly of electronic systems and sofware development. The aim of the LembergHIGHTech Cluster is to promote the industry of Western Ukraine and to develop strategic cooperations with companies in Western Europe.
A Ugandan doctor, who contracted Ebola in Sierra Leone, survived after being flown to Germany for aggressive treatment involving a new drug under clinical development for vascular leakage [1]. Dr Timo Wolf and colleagues, from University Hospital Frankfurt in Germany, detail the successful intensive-care treatment the doctor received under biosafety level 4 conditions in an Article published in The Lancet.
On 28 September, 2014, the 38-year old doctor, who was in charge of an Ebola virus treatment unit in Lakka, Sierra Leone, developed a fever and diarrhoea. He tested positive for the virus on the same day. The doctor was airlifted to Frankfurt University Hospital on the 5th day of his illness and admitted to a specialised isolation unit.
Within 72 hours of admission he developed signs of vascular leakage and severe multi-organ failure, including the lungs, kidneys, and gastrointestinal tract. He was placed on a ventilator and on kidney dialysis, and was given antibiotics together with a 3-day course of an experimental drug called FX06—a fibrin-derived peptide [2] that has been shown to reduce vascular leakage and its complications in mice with Dengue hemorrhagic shock.
A marked improvement in vascular and respiratory function was seen under the combined measures of intensive care and drug treatment. After a 30-day observation period, no Ebola virus genetic material was detected in the patient’s blood plasma. The patient was released from hospital and is now with his family.
“Even though the patient was critically ill, we were able to support him long enough for his body to start antibody production and for the virus to be cleared by his body’s defences”*, explains Dr Wolf.
“In terms of improving treatment for Ebola patients, we have shown how intensive care medicine can successfully be applied under strict isolation conditions”, adds senior author Professor Zacharowski, head of the Department of Anaesthetics and Intensive Care Medicine at Frankfurt University Hospital.”*
The authors conclude by calling for FX06 to be evaluated in clinical trials.
Notes to Editors:
*Quotes direct from authors and cannot be found in text of Article.
[1] Vascular leakage is the loss of fluid from blood vessels into the tissue due to the damage of the “lining” of the vessels.
[2] FX06 is a peptide that binds to VE-cadherin, a target on the surfaces of endothelial cells (which form the inner cell layer of blood vessels), and is believed to have a role in stabilizing the endothelium.
Please note that the patient described in this Article wishes to remain anonymous, and is not available for interview.
For interviews with report author Dr Timo Wolf, Division of Infectious Diseases, University Hospital Frankfurt, Frankfurt, Germany, please contact the University Hospital Frankfurt Press Office T) +49 (0) 69 9776 9118 E) christian.dietzel@gloria-mundi.de
This Wednesday the university hospital in Frankfurt reported the successful treatment of an Ebola patient medically evacuated from Sierra Leon. The compound FX06, developed in Austria, was used by experts of the University Hospital of Frankfurt in the frame of a compassionate use after being approved by the ethic commission. FX06 could substantially contribute to the recovery of the patient. The substance had been developed by a scientist at the Vienna General Hospital (AKH) and has the potential to decisively influence the outcome of the Ebola infection.